A CASE REPORT AND LITERATURE REVIEW ON GRANULOMATOUS CONJUNCTIVITIS AND LYMPHOCUTANEOUS LESIONS ASSOCIATED WITH SPOROTRICHOSIS

Received 2023-04-06; Accepted 2023-07-10; Published 2024-01-02

Abstract

Sporotrichosis, a skin mycosis caused by Sporothrix sp., is a rarely reported condition in Malaysia. In this case report, we present a case of granulomatous conjunctivitis and lymphocutaneous lesions caused by sporotrichosis, along with a review of the relevant literature available on PUBMED. A 70-year-old woman presented with mucopurulent discharge from her left eye and nodular skin lesions on her face. She reported previous contact with her cat, which had recently died from sporotrichosis. Upon examination, the left eyelid was edematous, and there was conjunctival hyperemia. Multiple granulomatous lesions were observed in the bulbar conjunctiva, covered by the mucopurulent discharge. Additionally, erythematous and granulomatous nodules were present on the left periorbital area, extending to the left malar area, accompanied by ipsilateral lymphadenopathy. Based on clinical suspicion, a diagnosis of ocular and lymphocutaneous sporotrichosis was made. Treatment was initiated with oral itraconazole and topical fluconazole empirically. The conjunctival sample tested negative for Sporothrix schenckii. Histopathological examination of skin biopsy specimens revealed nonspecific granulomatous inflammation. After three months of antifungal treatment, the patient recovered completely without any ocular complications.